TUDCA+
TUDCA+
TUDCA+

TUDCA+

4.9
Rated 4.9 out of 5 stars
4.9 Stars (156 Reviews)

Helps Detoxify the Body*
Promotes Healthy Bile Flow*
Supports Liver Health*

A premium blend of TUDCA, milk thistle, and pterostilbene to support healthy liver function.*

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"My grandson sends me it. It's one of the few things I take where I can actually notice a difference."

Vivian B.

As Seen On
TUDCA+
Tudca+ is a complete supplement to help flush toxins from your body while supporting healthy liver function. Enhanced with milk thistle and pterostilbene, Tudca+ offers a multi-faceted approach for liver wellness, helping to restore healthy bile flow, encourage regeneration of liver cells, and reduce oxidative stress impacting the liver.*
advanced liver support*
Helps Detoxify the Liver*
Everything you consume is filtered through your liver, which can leave behind harmful residue. Tudca+ helps clear the liver bile ducts and increases bile flow, helping cleanse your liver of harmful particles.*
Helps Balance Liver Enzymes*
Elevated levels of liver enzymes are correlated with inflammation and damage to liver cells. Tudca+ helps balance liver enzymes and reduce inflammation, supporting the wellness of your liver.*
Regenerates Liver Tissue*
Inside the liver, there are many inactive adult stem cells with the capability to repair and regenerate liver tissue, when activated. Through improving function of the bile duct, Tudca+ helps activate adult stem cells, so they develop and restore liver tissue.*
TUDCA+
advanced liver support*
Tudca+ is a complete supplement to help flush toxins from your body while supporting healthy liver function. Enhanced with milk thistle and pterostilbene, Tudca+ offers a multi-faceted approach for liver wellness, helping to restore healthy bile flow, encourage regeneration of liver cells, and reduce oxidative stress impacting the liver.*
Helps Detoxify the Liver*
Everything you consume is filtered through your liver, which can leave behind harmful residue. Tudca+ helps clear the liver bile ducts and increases bile flow, helping cleanse your liver of harmful particles.*
Helps Balance Liver Enzymes*
Elevated levels of liver enzymes are correlated with inflammation and damage to liver cells. Tudca+ helps balance liver enzymes and reduce inflammation, supporting the wellness of your liver.*
Regenerates Liver Tissue*
Inside the liver, there are many inactive adult stem cells with the capability to repair and regenerate liver tissue, when activated. Through improving function of the bile duct, Tudca+ helps activate adult stem cells, so they develop and restore liver tissue.*
A New Standard in Supplements
Impeccable Manufacturing Standards
Every Humanx supplement is manufactured in a CGMP certified facility, this means every supplement:
  • Meets FDA quality standards
  • Contains premium quality ingredients
  • Crafted with exceptional processing methods
Third Party Testing

Humanx undergoes rigorous third-party testing because we value complete transparency and you can feel confident you know exactly what you're getting

Evidence Based Ingredients

Our ingredients are extensively studied with the world's leading scientists publishing their peer reviewed findings in the National Center of Biotechnical Information

A New Standard in Supplements

Impeccable Manufacturing Standards

Every Humanx supplement is manufactured in a CGMP certified facility, this means every supplement:

  • Meets FDA quality standards
  • Contains premium quality ingredients
  • Crafted with exceptional processing methods

Third Party Testing

Humanx undergoes rigorous third-party testing because we value complete trans parency and you can feel confident you know exactly what you're getting

Evidence Based Ingredients

Our ingredients are extensively studied with the world's leading scientists publishing their peer reviewed finding in the National Center of Biotechnical Information


4.9
Rated 4.9 out of 5 stars
Based on 156 reviews
Total 5 star reviews: 141 Total 4 star reviews: 13 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 0
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156 reviews
  • Gary S.
    Verified Buyer
    1 month ago
    Rated 5 out of 5 stars
    Liver Pain

    I have less liver swelling.

    Was this helpful?
  • chris c.
    Verified Buyer
    1 month ago
    Rated 5 out of 5 stars
    great service from supplier

    helps me with my liver.

    Was this helpful?
  • Scott H.
    Verified Buyer
    2 months ago
    Rated 5 out of 5 stars
    Excellent product!

    Within a week of taking this my energy and digestion has improved!

    Was this helpful?
  • Katndog
    Flag of United States
    Verified Buyer
    6 months ago
    Rated 5 out of 5 stars
    I'm hooked

    Seems I can't go more than 3-4 days without this product. I learned that gallbladder stagnation symptoms can express themselves in right shoulder/neck pain along with sluggish digestion. Within a few hours of taking I can feel a softening in my abdomen as in less stressed out if that makes sense. The shoulder/neck pain greatly reduced or gone. I've since discovered B1 thiamine HCL. Combining the two along with magnesium and potassium has greatly improved my digestion!!!

    Tudca and thiamine HCL are game changers for me.

    Was this helpful?
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References

  1. Portincasa P, et al.  Effect of tauroursodeoxycholic acid on serum liver enzymes and dyspeptic symptoms in patients with chronic active hepatitis. Current Therapeutic Research. 1993.
  2. Sawitza, I., Kordes, C., Götze, S. et al.Bile acids induce hepatic differentiation of mesenchymal stem cells. Sci Rep. 2015. 
  3. Kusaczuk M. Tauroursodeoxycholate-Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives. Cells. 2019.
  4. Li S, Tan HY, Wang N, et al. Substitutes for Bear Bile for the Treatment of Liver Diseases: Research Progress and Future Perspective. Evid Based Complement Alternat Med. 2016.
  5. Wang W, Zhao J, Gui W, et al. Tauroursodeoxycholic acid inhibits intestinal inflammation and barrier disruption in mice with non-alcoholic fatty liver disease. Br J Pharmacol. 2018. 
  6. Pan XL, Zhao L, Li L, Li AH, Ye J, Yang L, Xu KS, Hou XH. Efficacy and safety of tauroursodeoxycholic acid in the treatment of liver cirrhosis: a double-blind randomized controlled trial. J Huazhong Univ Sci Technolog Med Sci. 2013. 
  7. Cruz-Ramón V, Chinchilla-López P, Ramírez-Pérez O, Méndez-Sánchez N. Bile Acids in Nonalcoholic Fatty Liver Disease: New Concepts and therapeutic advances. Ann Hepatol. 2017.
  8. Song Q, et al. The beneficial effects of taurine in alleviating fatty liver disease. Jour of Func Fo. 2021. 
  9. Kim, D.J., Yoon, S., Ji, S. et al.Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction. Sci Rep. 2018.
  10. Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in Liver Diseases: A Review of Their Mechanisms of Action and Clinical Applications. Handb Exp Pharmacol. 2019.
  11. Bodewes F, et al. Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr) in mice. Gast and Liver Phys. 2012.
  12. Nathanson M, et al. Stimulation of ATP secretion in the liver by therapeutic bile acids. Biochem Jour. 2001.
  13. Panella C, Ierardi E, De Marco MF, Barone M, Guglielmi FW, Polimeno L, Francavilla A. Does tauroursodeoxycholic acid (TUDCA) treatment increase hepatocyte proliferation in patients with chronic liver disease? Ital J Gastroenterol. 1995 .
  14. McCormack D, McFadden D. A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev. 2013.
  15. Youdim KA, Shukitt-Hale B, MacKinnon S, Kalt W, Joseph JA. Polyphenolics enhance red blood cell resistance to oxidative stress: in vitro and in vivo. Biochim Biophys Acta. 2000.
  16. Mikstacka R, Rimando AM, Ignatowicz E. Antioxidant effect of trans-resveratrol, pterostilbene, quercetin and their combinations in human erythrocytes in vitro. Plant Foods Hum Nutr. 2010.
  17. Fan X, Wang L, Huang J, Lv H, Deng X, Ci X: Pterostilbene Reduces Acetaminophen-Induced Liver Injury by Activating the Nrf2 Antioxidative Defense System via the AMPK/Akt/GSK3β Pathway. Cell Physiol Biochem. 2018.
  18. Gillessen A, Schmidt HH. Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review. Adv Ther. 2020.
  19. Trappoliere M, Caligiuri A, Schmid M, et al. Silybin, a component of sylimarin, exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells. J Hepatol. 2009.
  20. Pradhan SC, Girish C. Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine. Indian J Med Res. 2006.