Sulforaphane

Rated 5.0 out of 5
Based on 84 reviews

Detoxifies the body*
Activates Antioxidant Protection*
The Nutrient Responsible for the Health Benefits of Broccoli*

A phytochemical found in green vegetables responsible for many health benefits associated with eating broccoli, kale, and other cruciferous vegetables.*

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"Still hate the taste of broccoli. Luckily there's this instead with the stuff that actually matters."

David T.

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average rating 5.0 out of 5
Based on 84 reviews
  • 5 Stars
    81 Reviews
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99% of reviewers would recommend this product to a friend
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Review posted
Reviewed by tootieliza, from United States
Verified Buyer
Rated 5 out of 5

It does what it says

I was looking for something to help supplement my diet as I don t eat as much veggies as I should. This is wonderful! I have noticed that my bm has become regular I have more energy(I ve always been tired) and the best part is the mental clarity! I can actually focus! Highly recommend!

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Reviewed by Ashtyn, from United States
Verified Buyer
Rated 5 out of 5

Great!

This is great I don t have as much time on my hands to make healthy enough meals so these help me feel better about that. I also noticed more effective brain power I have more mental energy and the ability to focus was also improved a bit. I did not notice any odd taste or smell from the pills themselves.

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Reviewed by Mckenna W., from United States
Verified Buyer
Rated 5 out of 5

Impressed

Surprised at how much of a difference taking this has made. I don t get enough veggies all the time and this has helped make up for that.

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Reviewed by Maria, from United States
Verified Buyer
Rated 5 out of 5

Trusted ingredients and quality

This product arrived as expected in quality packaging. I ve been excited to use these since I am often experiencing brain funks and looking to improve my focus on work and tasks.

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References

  1. Arai Y, Martin-Ruiz CM, Takayama M, et al. Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians. EBioMedicine. 2015.
  2. Houghton CA. Sulforaphane: Its "Coming of Age" as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxid Med Cell Longev. 2019.
  3. Yoshida K, Ushida Y, Ishijima T, et al. Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World J Gastroenterol. 2015.
  4. Fahey JW, Zhang Y, Talalay P. Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA. 1997.
  5. Fahey JW, Talalay P. Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. Food Chem Toxicol. 1999.
  6. Zhang Y, Talalay P. Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes. Cancer Res. 1998.
  7. Boddupalli S, Mein JR, Lakkanna S, James DR. Induction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins a, C, and e. Front Genet. 2012.
  8. Dinkova-Kostova AT, Fahey JW, Kostov RV, Kensler TW. KEAP1 and Done? Targeting the NRF2 Pathway with Sulforaphane. Trends Food Sci Technol. 2017.
  9. Armah C.N., Derdemezis C., Traka M.H., Dainty J.R., Doleman J.F., Saha S. Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials. Molecular Nutrition Food Research. 2015.
  10. Dinkova-Kostova A.T., Abramov A.Y. The emerging role of NRF2 in mitochondrial function. Free Radical Biology and Medicine. 2015.
  11. Fahey J.W., Wehage S.L., Holtzclaw W.D., Kensler T.W., Egner P.A., Shapiro T.A. Protection of humans by plant glucosinolates: Efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora. Cancer Prevention Research. 2012.
  12. Hayes J.D., Dinkova-Kostova A.T. The NRF2 regulatory network provides an interface between redox and intermediary metabolism. Trends in Biochemical Sciences. 2014.
  13. Kubo, E., Chhunchha, B., Singh, P. et al.Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress. Sci Rep. 2017.
  14. Bai Y, Wang X, Zhao S, Ma C, Cui J, Zheng Y. Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation. Oxid Med Cell Longev. 2015.
  15. Xianglan Zhang, Xiao-Ou Shu, Yong-Bing Xiang, Gong Yang, Honglan Li, Jing Gao, Hui Cai, Yu-Tang Gao, Wei Zheng, Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality, The American Journal of Clinical Nutrition. 2011.
  16. Evans PC. The influence of sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease. EPMA J. 2011.
  17. Murashima M, Watanabe S, Zhuo XG, Uehara M, Kurashige A. Phase 1 study of multiple biomarkers for metabolism and oxidative stress after one-week intake of broccoli sprouts. Biofactors. 2004.
  18. Liu H, -J, Wang L, Kang L, Du J, Li S, Cui H, -X: Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells. Cell Physiol Biochem. 2018.
  19. Kim J, Lee S, Choi BR, Yang H, Hwang Y, Park JH, LaFerla FM, Han JS, Lee KW, Kim J. Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways. Mol Nutr Food Res. 2017.
  20. Zhang HQ, Chen SY, Wang AS, et al. Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization. Mol Nutr Food Res. 2016.