Sulforaphane+

Rated 5.0 out of 5
Based on 99 reviews

Supports Detoxification*
Promotes Antioxidant Activity*
Optimized with Moringa

A phytochemical found in green vegetables responsible for many health benefits associated with eating broccoli, kale, and other cruciferous vegetables.*

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"Still hate the taste of broccoli. Luckily there's this instead with the stuff that actually matters."

David T.

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average rating 5.0 out of 5
Based on 99 reviews
  • 5 Stars
    96 Reviews
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99% of reviewers would recommend this product to a friend
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Reviewed by John Wayne B., from United States
Verified Buyer
Rated 5 out of 5

Excellent addition to daily vitamins!!

Try it _ you will enjoy the benefits!!

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Reviewed by Pk, from United States
Verified Buyer
Rated 5 out of 5

Good as a pretreatment for hangovers

I'm not sure about increasing my productivity, but after taking this regularly, the intensity of hangovers after a fun night have drastically decreased.

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Reviewed by Peggy L. I., from United States
Verified Buyer
Rated 5 out of 5

Great High potency supplement

Great High potency supplement. It has cancer healing properties so Im told.

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Reviewed by Erik, from United States
Verified Buyer
Rated 5 out of 5

Good product and Good price for the dosage

Will order again

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References

  1. Arai Y, Martin-Ruiz CM, Takayama M, et al. Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians. EBioMedicine. 2015.
  2. Houghton CA. Sulforaphane: Its "Coming of Age" as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxid Med Cell Longev. 2019.
  3. Yoshida K, Ushida Y, Ishijima T, et al. Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World J Gastroenterol. 2015.
  4. Fahey JW, Zhang Y, Talalay P. Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA. 1997.
  5. Fahey JW, Talalay P. Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. Food Chem Toxicol. 1999.
  6. Zhang Y, Talalay P. Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes. Cancer Res. 1998.
  7. Boddupalli S, Mein JR, Lakkanna S, James DR. Induction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins a, C, and e. Front Genet. 2012.
  8. Dinkova-Kostova AT, Fahey JW, Kostov RV, Kensler TW. KEAP1 and Done? Targeting the NRF2 Pathway with Sulforaphane. Trends Food Sci Technol. 2017.
  9. Armah C.N., Derdemezis C., Traka M.H., Dainty J.R., Doleman J.F., Saha S. Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials. Molecular Nutrition Food Research. 2015.
  10. Dinkova-Kostova A.T., Abramov A.Y. The emerging role of NRF2 in mitochondrial function. Free Radical Biology and Medicine. 2015.
  11. Fahey J.W., Wehage S.L., Holtzclaw W.D., Kensler T.W., Egner P.A., Shapiro T.A. Protection of humans by plant glucosinolates: Efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora. Cancer Prevention Research. 2012.
  12. Hayes J.D., Dinkova-Kostova A.T. The NRF2 regulatory network provides an interface between redox and intermediary metabolism. Trends in Biochemical Sciences. 2014.
  13. Kubo, E., Chhunchha, B., Singh, P. et al.Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress. Sci Rep. 2017.
  14. Bai Y, Wang X, Zhao S, Ma C, Cui J, Zheng Y. Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation. Oxid Med Cell Longev. 2015.
  15. Xianglan Zhang, Xiao-Ou Shu, Yong-Bing Xiang, Gong Yang, Honglan Li, Jing Gao, Hui Cai, Yu-Tang Gao, Wei Zheng, Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality, The American Journal of Clinical Nutrition. 2011.
  16. Evans PC. The influence of sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease. EPMA J. 2011.
  17. Murashima M, Watanabe S, Zhuo XG, Uehara M, Kurashige A. Phase 1 study of multiple biomarkers for metabolism and oxidative stress after one-week intake of broccoli sprouts. Biofactors. 2004.
  18. Liu H, -J, Wang L, Kang L, Du J, Li S, Cui H, -X: Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells. Cell Physiol Biochem. 2018.
  19. Kim J, Lee S, Choi BR, Yang H, Hwang Y, Park JH, LaFerla FM, Han JS, Lee KW, Kim J. Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways. Mol Nutr Food Res. 2017.
  20. Zhang HQ, Chen SY, Wang AS, et al. Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization. Mol Nutr Food Res. 2016.