Spermidine+

Rated 5.0 out of 5
Based on 50 reviews

Aids the Cell Renewal Process*
Promotes Longevity*
Supports Healthy Aging*

A compound linked to longevity.*

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"My wife and I started with a different brand but prefer this one."

Mark R.

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average rating 5.0 out of 5
Based on 50 reviews
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Reviewed by Michael Giguere VINE V., from United States
Verified Buyer
Rated 5 out of 5

Works as advertised

Love it

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Reviewed by Dan M., from United States
Verified Buyer
Rated 5 out of 5

Notable Improvement in Recovery!

I was a bit skeptical at first, but started taking these every morning, and also right before a workout. There's been a noticeable improvement in my recovery! If I would run 5 miles, usually it would take at least 3 days until I felt strong enough to get back out there, but now I'm ready to roll the next day. Definitely would recommend, a great product at a great value!

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Reviewed by USA S., from United States
Verified Buyer
Rated 5 out of 5

Tried several and this works!!

I have tried several other brands and after a couple of weeks. This works.

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Reviewed by JS, from United States
Verified Buyer
Rated 5 out of 5

Already working!

I did some research ion all of the positive potential benefits of Spermadine so I decided to try it. I use other HumanX products because of the quality and even though I just started taking this, I already feel like it is helping with workout recovery.

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References

  1. Madeo F, et al. Spermidine delays aging in humans. Aging. 2018.
  2.  Madeo F, Bauer MA, Carmona-Gutierrez D, Kroemer G. Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? Autophagy. 2019.
  3.  Madeo F, Eisenberg T, Büttner S, Ruckenstuhl C, Kroemer G. Spermidine: a novel autophagy inducer and longevity elixir. Autophagy. 2010.
  4. Eisenberg T,et al. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. 2009.
  5. Aman Y, Schmauck-Medina T, et al. Autophagy in healthy aging and disease. Nat Aging. 2021.
  6. Ni YQ, Liu YS. New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases. Aging Dis. 2021.
  7. Ghosh I, et al. Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders. Neuropeptides. 2020.
  8. Gupta VK, et al. Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner. Nat Neurosci. 2013.
  9. Yang, Xin et al. Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans. Aging. 2020.
  10. Büttner S, et al. Spermidine protects against α-synuclein neurotoxicity. Cell Cycle. 2014.
  11. Kiechl S, et al. Higher spermidine intake is linked to lower mortality: a prospective population-based study. Amer J Cli Nutr. 2018.
  12.  Eisenberg T, et al. Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med. 2016.
  13. LaRocca TJ,et al. The autophagy enhancer spermidine reverses arterial aging. Mech Ageing Dev. 2013.
  14. Willeit P, et al. Telomere length and risk of incident cancer and cancer mortality. JAMA. 2010.
  15. Gupta VK, et al. Spermidine suppresses age-associated memory impairment by preventing adverse increase of presynaptic active zone size and release. PLoS Biol. 2016.