NMN

Rated 4.9 out of 5
Based on 86 reviews

Supports healthy levels of NAD+*
Supports healthy aging*
Great addition for your longevity routine

NMN supports NAD+ production and longevity.*

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    "NMN is my go to for getting rid of early morning brain fog, keeping my head clear and productive from the start of the day"

    John S.

    As Seen On

    A New Standard in Supplements


    average rating 4.9 out of 5
    Based on 86 reviews
    • 5 Stars
      79 Reviews
    • 4 Stars
      4 Reviews
    • 3 Stars
      3 Reviews
    • 2 Stars
      0 Reviews
    • 1 Star
      0 Reviews
    97% of reviewers would recommend this product to a friend
    Customer photos and videos
    Review posted
    Reviewed by manly
    Rated 5 out of 5

    As described by humanx

    Product does what it claims, happy and returning customer :)

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    Reviewed by gaming
    Rated 5 out of 5

    NMN is the real deal

    This NMN by humanx is working great for my wife and I, we have been taking it for about a year! Great natural energy and well being

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    Reviewed by ron
    Rated 5 out of 5

    NAD levels increased

    I took 4 bottles over 4 months and went for an NAD test and it is working really well

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    Reviewed by keelan
    Rated 5 out of 5

    Awesome nmn

    I've been taking NMN now for a few weeks I have noticed definite better mental clarity and a boost in my regular energy levels. I'm a huge fan of humanx products they are always pure with no extra fillers snuck in which is important to me. This is just another great product but this company.

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    References

    1. Bonkowski MS, at al. Slowing ageing by design: the rise of NAD+and sirtuin-activating compounds. Nat Rev Mol Cell Biol. 2016.
    2. Hong W, et al. Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism. Fr Cell Dev Bio. 2020.
    3. Bertoldo, M, et al. Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide.  Reprod. 2018.
    4. Frederick, D. W., Loro, E., Liu, L., Davila, A. Jr., Chellappa, K., Silverman, I. M., et al. Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle. Cell Metab. 2016.
    5. Imai S, et al. NAD+ and sirtuins in aging and disease. Metab. 2014.
    6. Imai S, et al. The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing. Metab. 2013.
    7. Kane A, et al. Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases. Circ Res. 2018.
    8. Lautrup S, et al. NAD+in Brain Aging and Neurodegenerative Disorders. Cell Metab. 2019.
    9. Wu LE, et al. The elusive NMN transporter is found. Nat Metab. 2019
    10. Covarrubias AJ, Perrone R, et al. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021.
    11. Liu J, Zong Z, Zhang W, Chen Y, Wang X, Shen J, Yang C, Liu X, Deng H. Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress viaDecreasing COX-2 Expression in Macrophages. Front Mol Biosci. 2021.
    12. Cantó, C., Menzies, K. J., and Auwerx, J. NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cel Metab. 2015.
    13. Guan, Y., Wang, S.-R., Huang, X.-Z., Xie, Q.-h., Xu, Y.-Y., Shang, D., et al. Nicotinamide Mononucleotide, an NAD+Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1–Dependent Manner.  Am. Soc. Nephrol. 2017.
    14. Haisheng H, et al. Adapting liposomes for oral drug delivery. Acta Pharmaceutica Sinica B. 2019.
    15. Amjad S, et al. Role of NAD+ in regulating cellular and metabolic signaling pathways. Mol Metab. 2021.
    16. Yoshino J, et al. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 2018.
    17. Ahn H, Park JH. Liposomal delivery systems for intestinal lymphatic drug transport. Biomater Res. 2016.
    18. Shade, CW. Liposomes as Advanced Delivery Systems for Nutraceuticals. Integr Med. 2016.
    19. Fang E, et al. NAD+replenishment improves lifespan and healthspan in ataxia telangiectasia models via mitophagy and DNA repairCell Metab. 2016.
    20. Mouchiroud L, et al. The NAD(+)/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling. Cell. 2013.