NMN

Rated 4.9 out of 5
Based on 87 reviews

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Supports healthy levels of NAD+*
Supports healthy aging*
Great addition for your longevity routine

NMN supports NAD+ production and longevity.*

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    "NMN is my go to for getting rid of early morning brain fog, keeping my head clear and productive from the start of the day"

    John S.

    As Seen On
    NMN
    NMN is the direct precursor to NAD+, a molecule linked to longevity. NAD+ has a critical role developing energy our body uses to function, through the processes known as cellular respiration. As we age, our NAD+ levels decline, however through supplementation, we can experience the benefits of NAD+.*
    unlock the power of NAD+
    Supports the Longevity Pathway
    NAD+ activates a family of proteins called Sirtuins; activation of Sirtuins is directly linked to longevity according to recent scientific research. Sirtuins are only active when NAD+ is present.*
    Supports Energy Production
    NAD+ has a major role helping convert nutrients into useable energy.*
    Direct Precursor of NAD+
    NMN is an immediate precursor to NAD+ helping support healthy NAD+ levels.*
    NMN
    unlock the power of NAD+
    NMN is the direct precursor to NAD+, a molecule linked to longevity. NAD+ has a critical role developing energy our body uses to function, through the processes known as cellular respiration. As we age, our NAD+ levels decline, however through supplementation, we can experience the benefits of NAD+.*
    Supports the Longevity Pathway
    NAD+ activates a family of proteins called Sirtuins; activation of Sirtuins is directly linked to longevity according to recent scientific research. Sirtuins are only active when NAD+ is present.*
    Supports Energy Production
    NAD+ has a major role helping convert nutrients into useable energy.*
    Direct Precursor of NAD+
    NMN is an immediate precursor to NAD+ helping support healthy NAD+ levels.*
    A New Standard in Supplements
    Impeccable Manufacturing Standards
    Every Humanx supplement is manufactured in a CGMP certified facility, this means every supplement:
    • Meets FDA quality standards
    • Contains premium quality ingredients
    • Crafted with exceptional processing methods
    Third Party Testing

    Humanx undergoes rigorous third-party testing because we value complete transparency and you can feel confident you know exactly what you're getting

    Evidence Based Ingredients

    Our ingredients are extensively studied with the world's leading scientists publishing their peer reviewed findings in the National Center of Biotechnical Information

    A New Standard in Supplements

    Impeccable Manufacturing Standards

    Every Humanx supplement is manufactured in a CGMP certified facility, this means every supplement:

    • Meets FDA quality standards
    • Contains premium quality ingredients
    • Crafted with exceptional processing methods

    Third Party Testing

    Humanx undergoes rigorous third-party testing because we value complete trans parency and you can feel confident you know exactly what you're getting

    Evidence Based Ingredients

    Our ingredients are extensively studied with the world's leading scientists publishing their peer reviewed finding in the National Center of Biotechnical Information


    average rating 4.9 out of 5
    Based on 87 reviews
    • 5 Stars
      80 Reviews
    • 4 Stars
      4 Reviews
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      3 Reviews
    • 2 Stars
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      0 Reviews
    97% of reviewers would recommend this product to a friend
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    Review posted
    Reviewed by Warhead, from United States
    Verified Buyer
    Rated 5 out of 5

    wait this is for sleep?

    this stuff gives me bursts of productive energy, it's great!

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    Review posted
    Reviewed by manly
    Rated 5 out of 5

    As described by humanx

    Product does what it claims, happy and returning customer :)

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    Review posted
    Reviewed by gaming
    Rated 5 out of 5

    NMN is the real deal

    This NMN by humanx is working great for my wife and I, we have been taking it for about a year! Great natural energy and well being

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    Review posted
    Reviewed by ron
    Rated 5 out of 5

    NAD levels increased

    I took 4 bottles over 4 months and went for an NAD test and it is working really well

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    References

    1. Bonkowski MS, at al. Slowing ageing by design: the rise of NAD+and sirtuin-activating compounds. Nat Rev Mol Cell Biol. 2016.
    2. Hong W, et al. Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism. Fr Cell Dev Bio. 2020.
    3. Bertoldo, M, et al. Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide.  Reprod. 2018.
    4. Frederick, D. W., Loro, E., Liu, L., Davila, A. Jr., Chellappa, K., Silverman, I. M., et al. Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle. Cell Metab. 2016.
    5. Imai S, et al. NAD+ and sirtuins in aging and disease. Metab. 2014.
    6. Imai S, et al. The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing. Metab. 2013.
    7. Kane A, et al. Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases. Circ Res. 2018.
    8. Lautrup S, et al. NAD+in Brain Aging and Neurodegenerative Disorders. Cell Metab. 2019.
    9. Wu LE, et al. The elusive NMN transporter is found. Nat Metab. 2019
    10. Covarrubias AJ, Perrone R, et al. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021.
    11. Liu J, Zong Z, Zhang W, Chen Y, Wang X, Shen J, Yang C, Liu X, Deng H. Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress viaDecreasing COX-2 Expression in Macrophages. Front Mol Biosci. 2021.
    12. Cantó, C., Menzies, K. J., and Auwerx, J. NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cel Metab. 2015.
    13. Guan, Y., Wang, S.-R., Huang, X.-Z., Xie, Q.-h., Xu, Y.-Y., Shang, D., et al. Nicotinamide Mononucleotide, an NAD+Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1–Dependent Manner.  Am. Soc. Nephrol. 2017.
    14. Haisheng H, et al. Adapting liposomes for oral drug delivery. Acta Pharmaceutica Sinica B. 2019.
    15. Amjad S, et al. Role of NAD+ in regulating cellular and metabolic signaling pathways. Mol Metab. 2021.
    16. Yoshino J, et al. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 2018.
    17. Ahn H, Park JH. Liposomal delivery systems for intestinal lymphatic drug transport. Biomater Res. 2016.
    18. Shade, CW. Liposomes as Advanced Delivery Systems for Nutraceuticals. Integr Med. 2016.
    19. Fang E, et al. NAD+replenishment improves lifespan and healthspan in ataxia telangiectasia models via mitophagy and DNA repair. Cell Metab. 2016.
    20. Mouchiroud L, et al. The NAD(+)/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling. Cell. 2013.