Spermidine+
Spermidine+
Spermidine+

Spermidine+

5.0
Rated 5.0 out of 5 stars
5.0 Stars (65 Reviews)

Aids the Cell Renewal Process*
Promotes Longevity*
Supports Healthy Aging*

A compound linked to longevity.*

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"My wife and I started with a different brand but prefer this one."

Mark R.

As Seen On
Spermidine+
spur-mih-deen
Spermidine is a polyamine making waves in the scientific community for its incredible benefits for health and longevity. Spermidine appears to be linked to many critical biological functions that influence lifespan.*
for healthy aging*
Supports the Cell Renewal Process
Autophagy is our body's cell renewal process, a critical process linked to health and longevity. When autophagy takes place, old and dysfunctional cells are recycled, in order to prioritize the growth of young and vital cells.*
Supports the Mitochondrial Renewal Process
Mitophagy refers to the recycling process of damaged mitochondria. This is a critical function for the health and integrity of the cell, as mitochondria are responsible for generating energy for the body.*
Supports Heart Health
Spermidine supplementation supports the structural integrity and sensitivity of cardiomyocytes, the cells of the heart that make it contract. Through a combination of many factors, such as Spermidine's ability to help maintain structure of heart cells and its ability to support the cell renewal process, scientists report that Spermidine displays cardioprotective benefits.*
Spermidine+
spur-mih-deen
for healthy aging*
Spermidine is a polyamine making waves in the scientific community for its incredible benefits for health and longevity. Spermidine appears to be linked to many critical biological functions that influence lifespan.*
Supports the Cell Renewal Process
Autophagy is our body's cell renewal process, a critical process linked to health and longevity. When autophagy takes place, old and dysfunctional cells are recycled, in order to prioritize the growth of young and vital cells.*
Supports the Mitochondrial Renewal Process
Mitophagy refers to the recycling process of damaged mitochondria. This is a critical function for the health and integrity of the cell, as mitochondria are responsible for generating energy for the body.*
Supports Heart Health
Spermidine supplementation supports the structural integrity and sensitivity of cardiomyocytes, the cells of the heart that make it contract. Through a combination of many factors, such as Spermidine's ability to help maintain structure of heart cells and its ability to support the cell renewal process, scientists report that Spermidine displays cardioprotective benefits.*
A New Standard in Supplements
Impeccable Manufacturing Standards
Every Humanx supplement is manufactured in a CGMP certified facility, this means every supplement:
  • Meets FDA quality standards
  • Contains premium quality ingredients
  • Crafted with exceptional processing methods
Third Party Testing

Humanx undergoes rigorous third-party testing because we value complete transparency and you can feel confident you know exactly what you're getting

Evidence Based Ingredients

Our ingredients are extensively studied with the world's leading scientists publishing their peer reviewed findings in the National Center of Biotechnical Information

A New Standard in Supplements

Impeccable Manufacturing Standards

Every Humanx supplement is manufactured in a CGMP certified facility, this means every supplement:

  • Meets FDA quality standards
  • Contains premium quality ingredients
  • Crafted with exceptional processing methods

Third Party Testing

Humanx undergoes rigorous third-party testing because we value complete trans parency and you can feel confident you know exactly what you're getting

Evidence Based Ingredients

Our ingredients are extensively studied with the world's leading scientists publishing their peer reviewed finding in the National Center of Biotechnical Information


5.0
Rated 5.0 out of 5 stars
Based on 65 reviews
Total 5 star reviews: 65 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
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65 reviews
  • Maria Elena M.
    Verified Buyer
    6 months ago
    Rated 5 out of 5 stars
    Excelente

    Muy buena calidad (Very good quality)

    Was this helpful?
  • RyanJ
    Flag of United States
    Verified Buyer
    1 year ago
    Rated 5 out of 5 stars
    Boost of Wellness

    After taking these for the first couple of days, I began to feel a vibrance from them.

    Driving to work in the mornings, I've felt a new enthusiasm. I've found myself with my volume up and singing loudly. I for sure see myself keeping these stocked in my house.

    Was this helpful?
  • Loving i.
    Flag of United States
    Verified Buyer
    1 year ago
    Rated 5 out of 5 stars
    So far so good

    I've been using this daily for about a week now and I've observed a significant improvement in my energy levels. Although it has only been about a week it appears to be working well!

    Was this helpful?
  • Matthew H.
    Flag of United States
    Verified Buyer
    1 year ago
    Rated 5 out of 5 stars
    Working well! Loving it’s Vegan and Non-GMO

    This product has been working well for me so far. My favorite part is that it is non-GMO, vegan friendly, and doesn't contain a lot of the junk that other competitors are using. I'm excited to hopefully see continued improvements the longer I take this product.

    Was this helpful?
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References

1. Madeo F, et al. Spermidine delays aging in humans. Aging. 2018.

2. Madeo F, Eisenberg T, Büttner S, Ruckenstuhl C, Kroemer G. Spermidine: a novel autophagy inducer and longevity elixir. Autophagy. 2010.

3. Eisenberg T,et al. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. 2009.

4. Aman Y, Schmauck-Medina T, et al. Autophagy in healthy aging and disease. Nat Aging. 2021.

5. Ni YQ, Liu YS. New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases. Aging Dis. 2021.

6. Ghosh I, et al. Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders. Neuropeptides. 2020.

7. Gupta VK, et al. Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner. Nat Neurosci. 2013.

8. Yang, Xin et al. Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans. Aging. 2020.

9. Büttner S, et al. Spermidine protects against α-synuclein neurotoxicity. Cell Cycle. 2014.

10. Kiechl S, et al. Higher spermidine intake is linked to lower mortality: a prospective population-based study. Amer J Cli Nutr. 2018.

11. Eisenberg T, et al. Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med. 2016.

12. LaRocca TJ,et al. The autophagy enhancer spermidine reverses arterial aging. Mech Ageing Dev. 2013.

13. Willeit P, et al. Telomere length and risk of incident cancer and cancer mortality. JAMA. 2010.

14. Gupta VK, et al. Spermidine suppresses age-associated memory impairment by preventing adverse increase of presynaptic active zone size and release. PLoS Biol. 2016.